Prefrontal Cortical GABA Modulation of Spatial Reference and Working Memory
نویسندگان
چکیده
منابع مشابه
Prefrontal Cortical GABA Modulation of Spatial Reference and Working Memory
BACKGROUND Dysfunction in prefrontal cortex (PFC) GABA transmission has been proposed to contribute to cognitive dysfunction in schizophrenia, yet how this system regulates different cognitive and mnemonic functions remains unclear. METHODS We assessed the effects of pharmacological reduction of GABAA signaling in the medial PFC of rats on spatial reference/working memory using different vers...
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Prefrontal cortex (PFC) is involved in multiple functions including attentional , spatial orientation, short and long-term memory. Our previous study indicated that microinjection of testosterone in CA1 impaired spatial learning and memory. Some evidence suggests that impairment effect of testosterone is mediated by GABAergic system. In the present study, we investigated the interaction of test...
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Prefrontal cortex (PFC) is involved in multiple functions including attentional , spatial orientation, short and long-term memory. Our previous study indicated that microinjection of testosterone in CA1 impaired spatial learning and memory. Some evidence suggests that impairment effect of testosterone is mediated by GABAergic system. In the present study, we investigated the interaction of test...
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ژورنال
عنوان ژورنال: International Journal of Neuropsychopharmacology
سال: 2014
ISSN: 1469-5111,1461-1457
DOI: 10.1093/ijnp/pyu013